Christian McCaffrey suffered a knee injury and could miss the rest of the season

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"San Francisco" running back Christian McCaffrey left the game early against the "Buffalo Bills" (10:35) due to a knee injury.

After the game, Foothinners head coach Kyle Shanahan said McCaffrey injured his posterior cruciate ligament and could miss the rest of the season.

McCaffrey missed the first 8 games of the regular season due to an Achilles and calf muscle injury.

The running back has gained 49.7 yards per game in 3 games since returning from injured reserve.

The "Foothinners" are in last place in the NFC West with a 5-7 record.